Manuela Basso

Via Sommarive, 9 - 38123 Povo
tel. 0461 285219
manuela.basso[at]unitn [dot] it
Area CUN: Scienze biologiche (05)
Settore scientifico disciplinare: BIOLOGIA APPLICATA (BIO/13)

Formazione

01/09/2003 – 14/03/2008        Doctor of Philosophy (PhD) in Life Science, The Open University Milton Keynes/UK

01/09/1997 – 08/10/2002        Master of Science in Medical Biotechnology, School of Medicine, University of Torino, Torino, Italy

 

                                                

Carriera accademica ed attività didattica

Assistant Professor; Ricercatore RTD-A

Interessi di ricerca

The laboratory is generally interested in deciphering the pro-survival mechanisms linked to neuronal activity and the neuronal adaptive response to stress. 

Attività di ricerca

http://web.unitn.it/en/cibio/32974/laboratory-of-transcriptional-neurobiology

Appartenenza a società e comitati scientifici

2008- Present              Member, Society for Neuroscience

2013                            Member, International Society for Neurochemistry

2012                            Member, ISSNAF - Italian Scientists and Scholars in North America Foundation

2008- 2013                  Member, New York Academy of Sciences      

2001-2003                   Member, Italian Association for the Cure of Parkinson’s disease

Premi e riconoscimenti

08/10/2015 – 10/10/2015        Travel award for the SINS meeting, Cagliari, Italy.

27/03/2015 – 29/03/2015        Travel award for the 210th ENMC workshop, Nardeen, The Netherlands.

20/04/2013 – 24/04/2013        Travel award for the International Society of Neurochemistry, Cancun, Mexico and selected speaker for the Young Investigator Colloquia.

07/09/2012                              Poster award at the annual Burke Research Medical Institute contest, Weill Medical College, Cornell University, White Plains, NY, USA

01/09/2006 - 31/12/2007         PhD (Leonardi) Fellowship, Mario Negri Institute, Milan, Italy

01/09/2003 - 31/08/2006         PhD Fellowship from the Dulbecco Telethon Institute, Italy

08/10/2002                              Magna cum laude and Honors, University of Torino, Italy

01/10/1997 – 30/09/2002        EDISU Scholarship, Torino, Italy

1994                                        Rotary Club Scholarship, Ivrea, Italy

Convegni e conferenze

Selected List Of Conferences, Workshops And Seminars As A Presenter

May 31st -June 5th 2015: Partial amelioration of HD symptoms in R6/2 mice treated with CI-994, a class I selective HDAC inhibitor. GAC repeats Gordon Conference, Il Ciocoo, Italy. Poster presentation.

May 29th 2015: Mutant transglutaminase 6 mediated toxicity: a basis for neurodegeneration for spinocerebellar ataxia 35. Molecular Mechanisms of Neurodegeneration, Milan, Italy. Poster presentation.

March 20th 2015: Transglutaminases and the neuronal adaptive response. University of Nottingham, UK, Invited speaker.

July 2014: Understanding transglutaminase upregulation in neuronal stress. Gordon Research Conference “Transglutaminase in Human Disease Conditions” 2014, Il Ciocco, Italy. Invited Speaker.

May 2013: External Review of the Program project P01 NIA AG014930 funded by NIH. Oral presentation.

April 2013: Transglutaminase inhibition abrogates oxidative stress-mediated and excitotoxic death: a new epigenetic modulator on the CNS block. ISN 2013, Cancun. Invited Speaker for the Young Investigator Colloquia.

December 2012: University of Trento. Transglutaminase 2 as a novel candidate modulator of metabolic gene transcription. Invited Seminar.

December 2012: International Symposium on ALS/MND Chicago, USA. Proteomic analysis of astrocytes and conditioned media from the G93A SOD1 mouse model of amyotrophic lateral sclerosis reveals secretory pathway alterations. Poster presentation. The poster was selected for the final Highlights of the meeting.

October 2012: University of Kansas. Transglutaminase 2 as a novel candidate modulator of metabolic gene transcription. Invited Seminar.

September 2012: Burke poster presentation. Transglutaminase inhibition protects against oxidative stress-mediated neuronal death downstream of pathological ERK activation. Poster presentation. Winner of the second prize for best posters presented.

July 2012: Transglutaminase in the nucleus: novel targets for an old enzyme. Gordon Research Conference “Transglutaminase in Human Disease Conditions” 2012, Davidson College, NC. Invited Speaker on Behalf of Dr. Rajiv R. Ratan.

July 2012: Research Gordon Conference “Transglutaminase in Human Disease Conditions” 2012, Davidson College, NC, USA. Transglutaminase inhibition protects against oxidative stress-mediated neuronal death downstream of pathological ERK activation. Poster presentation.

September 2011: Adaptation to Mitochondrial Dysfunction in Alzheimer's Disease and Huntington's Disease Via Inhibition of Transglutaminase 2. 5th Neurodegenerative Conditions Research and Development 2011, San Francisco, CA. Invited Speaker.

June 2011: Polyamines Gordon Research Conference, NH, USA. Adaptation to mitochondrial dysfunction in Huntington's disease via inhibition of Transglutaminase 2. Poster presentation.

April 2011: External Review of the Program project P01 NIA AG014930 funded by NIH. Oral presentation.

Altre attività

Supervision Of Graduate Students And Postdoctoral Fellows

2015                            2 Postdoctoral Fellows, 2 Master Students and 1 Bachelor student

2014                            1 Postdoctoral Fellow, 1 Master Student and 1 Summer student

2012- 2013                  2 Postdoctoral Fellows and 1 Technician

2009-2012                   1 Graduate Student, 1 Technician and 2 Summer students

2005-2007                   1 Master Student         

 

Organisation Of Scientific Meetings

30/09/2013 – 04/10/2013        Scientific Organizer, AxAlpS, The core of neuronal communication: axonal biology, degeneration and regeneration/ Cavalese (TN), Italy

23/01/2006 – 25/01/2006        Member of the Scientific Committee, 4th Joint PhD Student Workshop / Riva del Garda (TN), Italy

 

Institutional Responsibilities

01/04/2012 – 31/10/2013        Faculty member (Instructor), Weill Medical College, Cornell University/ New York/ USA

01/04/2011 - 30/06/2012         Graduate Student Advisor, Weill Medical College, Cornell University/ New York/ USA

2014-2015                               Member of Selection Committees at the University of Trento, CIBIO, Italy

10-12/12/2014                         PhD evaluation Committee University of Trento, CIBIO

2014-2015                               Delegate for CIBIO at the CLA, University of Trento

 

Commissions Of Trust

2015                            Reviewer for the Journal: eNeuro, Neuroscience, Glia

2014                            Reviewer for the Journal: Proteomics, Journal of Developmental Neuroscience, La Prensa Medica, The Journal of Neuroscience, Cell&Death Differentiation

2012-2013                   Reviewer for the Journal: The Journal of Neuroscience, Antioxidants & Redox Signaling, Cell Biology and Toxicology, British Journal of Pharmacology, Molecular and Cellular Neuroscience, FASEB Journal, Amino Acids, Recent patents on CNS drug discovery

2012-2015                   Grant Reviewer for: Alzheimer’s Association (2012 and 2013, 2014, 2015), Croatian Science Foundation (2012), Italian Ministry of Education (PRIN and Future and Research 2013)

2009-2012                   Reviewer for the Journal: Journal of Neuroscience, Neurobiology of Disease, Antioxidants & Redox Signaling, Neuroscience

2011                            Scientific Advisory Board for the GTC’s Biomarker Europe    Summit (September 5th-7th, 2012, Zurich, Switzerland)