Enrico Domenici
Formazione |
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1986-90 Ph.D. in Molecular Sciences/Chemistry with full honors at the Scuola Normale Superiore, University of Pisa (70/70 cum laude) 1980-84 University of Pisa, Italy; Faculty of Sciences. Degree in Biological Sciences (Laurea) with full honors (110/110 cum laude) |
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Carriera accademica ed attività didattica |
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Oct 15 – present Associate Professor, Centre for Integrative Biology, University of Trento In charge for the Course in “Genomics in drug discovery” (6ECTS), organized by the Center for Integrative Biology (CIBIO) for the Master in Cellular and Molecular Biotechnology, University of Trento (from academic years 2012/3 – present). The course is aimed at providing the basis for the understanding of modern proteomic and genomic applications, including high-throughput biology platforms, to drug development, from target identification to clinical biomarker development Invited lecturer at the International Master Degree in Neuroscience, a two-year multidisciplinary training in neurobiology at the Brain Centre for Neuroscience (Trieste), since 2009 |
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Interessi di ricerca |
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Genomic and proteomic biomarkers in neuroscience (depression, schizophrenia and autism, neurodegenerative disorders); functional genomics at genome-wide level; identification of novel targets through integrative genomic and proteomic analysis. |
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Attività di ricerca |
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Sept 12-Sept 15 Molecular Biomarker Leader; Neuroscience, Ophthalmology and Rare Disorders DTA, Roche, Basel Oct 10-Aug 12 Head of Biomarker and Pathway Analysis for CNS, Translational Research Sciences, Roche, Basel Oct 08-Sept 10 Translational Medicine Leader, Center of Excellence for Drug Discovery in Neuroscience, GSK, Verona Sept 04-Sept 08 Director of Molecular Psychiatry, Center of Excellence for Drug Discovery in Psychiatry, GSK, Verona Jan 00-Aug 04 Director of Molecular Diagnostic/Molecular Medicine, GSK Medicines Research Center, Verona Oct 94 -Dec 99 Head of Molecular Microbiology/Microbial Biochemistry, GlaxoWellcome Medicines Research Center, Verona Oct 90-Sep 94 Research Scientist, Glaxo Medicines Research Center, Verona 1987-Sep 90 ENI fellowship for a PhD at the Scuola Normale Superiore di Pisa, Department of Chemistry and Pharmaceutical Chemistry (University of Pisa), and Pharmaceutical Division of St. Jude Children Research Hospital, Memphis, TN (USA) 1986-1987 Mario Negri Pharmacological Research Institute, Milano, trainee 1982-84 Department of Biochemistry, University of Pisa (student fellow) |
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Appartenenza a società e comitati scientifici |
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Reviewing and Editorial Activity
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Altre attività |
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Responsibility for Collaborations with Academic Institutions (Last 10 Years)
Capacity to attract external research grants and Coordination of Corresponding Projects Presented proposals to obtain funding from the European Community for the following research programmes:
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Note |
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Short Biography 20+ years of experience in research and drug discovery in different therapeutic areas, ranging from the identification of novel targets and development of high-throughput screen programs to the application of genomic biomarkers in clinical settings. Led a number of early drug discovery projects in different therapy areas. Since 2000, increased focus on the discovery of biomarkers in neuroscience by a combination of genetic, genomic and proteomic approaches in preclinical and clinical context. In 2004, took accountability for the biomarker strategy of psychiatry at GlaxoSmithKline. In 2010 joined Roche Neuroscience, leading the implementation of molecular biomarkers in neuroscience first as Biomarker and Pathway Analysis Area Head and later as Molecular Biomarker Leader. In 2015, joined the University of Trento, Centre for Integrative Biology, as Associate Professor. During his scientific career, Enrico Domenici has established a number of research collaborations with academic partners and with precompetitive consortia and has supervised a number of Master and PhD students. |